NiÃ±o Inocente (Miguel Tanfelix) is a fun-loving teenager who is close to his family and friends and was brought up by his adoptive parents, David and Leny Inocente, to be righteous and obedient. NiÃ±o, a mentally-challenged teenager, learns how to overcome obstacles along with his best friends, Tukayo (David Remo), who is unknowingly the Santo NiÃ±o (theÂ Infant Jesus), and Gracie (Bianca Umali), on whom he later develops a crush, and continues to inspire his community with his good teachings. The prominent Sagrado family of Barangay Pag-asa is close with NiÃ±o, especially Hannah, unknowingly to her is NiÃ±o's real mother. Hannah hopes to be reunited with her long-lost son one day, who was separated from her. There are still many negative forces in Barangay Pag-asa, such as the Santoses and Lucio, the Sagrado's loyal but scheming assistant. NiÃ±o and his father, Gabriel were separated from Hannah during an ambush caused by Lucio. The whole community gradually learns from their mistakes to become better, kind-hearted people and to stay strong in their faith.